As of
June 30, 2026

As of
December 31, 2025

(in thousands)

Product revenue related reserves

$

118,639

$

117,518

Accrued contract manufacturing costs

41,256

92,281

Accrued employee compensation costs

40,972

58,607

Accrued litigation contingency charge

39,000

—

Accrued professional fees

20,874

17,840

Accrued interest expense

15,847

20,714

Accrued clinical and pre-clinical costs

15,308

18,894

Accrued royalties

10,200

10,863

Accrued income taxes

9,309

4,755

Accrued clinical collaboration costs

5,155

10,222

Accrued milestone costs

3,200

1,000

Other

5,472

6,965

Total accrued expenses

$

325,232

$

359,659