v3.26.1
Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2026
Jun. 30, 2025
Cash flows from operating activities    
Net loss $ (150,645) $ (79,457)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 5,007 5,346
Accretion of discount on marketable debt securities, net (135) (1,489)
Stock-based compensation 18,753 22,950
Loss (gain) on sale of marketable securities, net 2 (5,380)
Change in fair value of marketable equity securities 33,865 (528)
Asset impairment charges 797 6,723
Non-cash royalty revenue related to the sale of future royalties (17,201) (36,831)
Non-cash interest expense on liabilities related to the sale of future royalties 12,048 16,906
Changes in operating assets and liabilities:    
Accounts receivable (22,636) 14,636
Prepaid expenses and other assets (1,427) 3,504
Accounts payable 1,634 3,810
Accrued expenses 1,471 2,631
Operating lease, net (1,180) 877
Other assets and liabilities, net (3,639) (6,287)
Net cash used in operating activities (123,286) (52,589)
Cash flows from investing activities    
Purchase of marketable debt securities (72,679) (176,810)
Purchase of property and equipment (1,148) (1,827)
Proceeds from sales of marketable equity securities 0 13,399
Proceeds from sales of marketable debt securities 30,658 0
Proceeds from maturities of marketable debt securities 154,966 219,382
Net cash provided by investing activities 111,797 54,144
Cash flows from financing activities    
Proceeds from the exercises of stock options 985 2,974
Proceeds from issuance of common stock under the Employee Stock Purchase Plan 996 662
Cash paid to acquire noncontrolling interest 0 (1,725)
Net cash provided by financing activities 1,981 1,911
Net (decrease) increase in cash, cash equivalents, and restricted cash (9,508) 3,466
Cash, cash equivalents, and restricted cash, beginning of period 54,362 41,262
Cash, cash equivalents, and restricted cash, end of period 44,854 44,728
Supplemental disclosure of cash flow information    
Interest paid 5 2
Income taxes paid:    
Federal 51 7,000
State 3,903 0
Foreign 180 0
Total $ 4,134 $ 7,000